NFL Leaders |
Rushing Yards Gained
| Rank | Name | Team | G | Rushes | Rush Yds | Yd/G | Avg | TD |
| 1 | C. McCaffrey | SF | 4 | 80 | 459 | 114.8 | 5.74 | 6 |
| 2 | D. Swift | Phi | 4 | 59 | 364 | 91.0 | 6.17 | 2 |
| 3t | J. Conner | Ari | 4 | 62 | 318 | 79.5 | 5.13 | 2 |
| 3t | B. Robinson | Atl | 4 | 53 | 318 | 79.5 | 6.00 | 0 |
| 5 | T. Pollard | Dal | 4 | 73 | 311 | 77.8 | 4.26 | 2 |
| 6 | D. Achane | Mia | 3 | 27 | 309 | 103.0 | 11.44 | 4 |
| 7 | J. Cook | Buf | 4 | 56 | 296 | 74.0 | 5.29 | 1 |
| 8 | D. Henry | Ten | 4 | 73 | 285 | 71.3 | 3.90 | 2 |
| 9 | K. Walker III | Sea | 4 | 64 | 283 | 70.8 | 4.42 | 5 |
| 10 | Z. Moss | Ind | 3 | 66 | 280 | 93.3 | 4.24 | 1 |
| 11 | I. Pacheco | KC | 4 | 55 | 270 | 67.5 | 4.91 | 2 |
| 12 | D. Montgomery | Det | 3 | 69 | 262 | 87.3 | 3.80 | 5 |
| 13 | B. Robinson Jr. | Was | 4 | 61 | 261 | 65.3 | 4.28 | 3 |
| 14 | T. Etienne Jr. | Jax | 4 | 69 | 260 | 65.0 | 3.77 | 1 |
| 15 | A. Mattison | Min | 4 | 56 | 250 | 62.5 | 4.46 | 0 |
| 16 | R. Mostert | Mia | 4 | 48 | 249 | 62.3 | 5.19 | 6 |
| 17 | J. Mixon | Cin | 4 | 59 | 247 | 61.8 | 4.19 | 1 |
| 18 | K. Williams | LAR | 4 | 64 | 245 | 61.3 | 3.83 | 5 |
| 19 | L. Jackson | Bal | 4 | 41 | 220 | 55.0 | 5.37 | 4 |
| 20t | B. Hall | NYJ | 4 | 32 | 210 | 52.5 | 6.56 | 0 |
| 20t | N. Harris | Pit | 4 | 49 | 210 | 52.5 | 4.29 | 0 |
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